In Science of Synthesis: Cross Coupling and Heck-Type

Reactions, expert authors present and discuss the best and most reliable

methods currently available for the formation of new carbon-carbon and

carbon-heteroatom bonds using these reactions, highlighted with representative

experimental procedures. Together, the three volumes of Cross Coupling and

Heck-Type Reactions













provide an extensive overview of

the current state of the art in this field of central

importance in modern chemistry, and are an invaluable resource for the practicing synthetic

organic chemist.



This volume provides comprehensive coverage of the different classes of

Heck-type reactions. It describes the state-of-the-art developments in each area

whilst critically evaluating the strengths and weaknesses of the different

methods. In accordance with the growing demand for synthetic efficiency and

practicality in organic synthesis, many of these newly developed Heck-type

methods feature operationally convenient conditions, high catalytic efficiency,

and high levels of chemical, regiochemical, and stereochemical control.

Metal-catalyzed C-H functionalization has also been developed into a powerful