Each of the places in Nashville Haunted Handbook is presented in a two-page spread that includes directions, a brief history, details about how the place is haunted, and advice on visiting the place. Each spread also includes one or two photos. The places are organized into sections, including schoolhouses, roads and bridges, hotels and inns, and others.

Nashville Haunted Handbook is written with the ghost enthusiast in mind. All 100 chapters contain information on the history as well as the haunting surrounding each location, as well as detailed directions on how to locate each site. Many of the chapters also contain insider information that only a local would know, making it easier for ghost hunters to investigate.