After being blamed for his wife's murder, the disappearance of his son leads a man to the discovery of a deadly tribe of women known as lamia, who propagate the earth with the seed of prominent men and kill them within the boundaries of an ancient curse.

Throughout the world, Maxwell Bunting patterns the lamia's insatiable appetite for eating boys, and in Virginia, the hunter not only finds love but also meets his prey as ancient documents reveal a prophesy that becomes present-day reality, bringing tragedy that only perseverance can resolve.