Every marriage is different. And family is more than blood.

Ava and Claire have moved on from the traumatic events of 1934 - while Ava has decided at last to marry patient Max Byrne and allow love back into her life, Claire and her husband have gone to France to repair their relationship. Harry encounters an old friend in Paris and offers to assist two Jewish refugees trying to flee a continent on the verge of war.

Back in Philadelphia, Ava navigates the challenges of being a doctor's wife while maintaining her independence. When Max becomes involved with recent refugees coming to his clinic, their lives intertwine with Harry Warriner's larger project.

In a time of tremendous upheaval, can the sisters find the strength to embrace the ever-changing relationships of marriage and family? Ava and Claire will discover that love and family can transcend blood and that true courage is not measured in action, but in the heart.