One of the great medical authorities of the early sixteenth century, Girolamo Fracastoro (1478--1553) was also a prominent Neo-Latin poet. This volume includes his famous didactic poem Syphilis in three books, which gave the name to the disease and contains the first poetical description of Columbus's discovery of America. Also included are a short Biblical epic, the Joseph, and the Carmina, a collection of shorter poetry in various metres. This volume presents an updated edition of all the Latin texts, two previously unpublished short poems, and the first complete translation into English of Fracastoro's Latin poetry.