A missing man, a stolen baby and a plot of land where nothing grows. Are they connected? One person knows.

1948: Sugar Creek seemed such a welcoming town for Ellen, a young woman keen to share the news of her pregnancy with her fiancé Billy. When Billy signs up for extra work testing topical creams at the local military base, to earn money for their wedding, Ellen is nervous. Now it seems her fears were founded. Billy has disappeared. Devastated, Ellen begins to ask questions, turning the locals against her and putting her life at risk as she desperately searches for him.

2000: Instead of beginning her career with a dream job as a GP in a suburban practice, Dana has found herself jobless and facing the hospital board for a mistake she made with a patient. Herb Hipworth, mayor of Sugar Creek, is desperate for a town doctor and makes Dana an offer she can't refuse. But when Dana arrives in the remote tropical town, she discovers the locals are plagued with unexplained health issues. Now, as she digs for the cause, she stumbles upon a decades-long conspiracy leading to an environmental disaster.