The Beast Keepers is the story of Jonathan F. St. Roche, a young veterinarian who takes a job in the rural Ohio town of Carrollton. He soon discovers it is a safe haven for a menagerie of mythical creatures (including a pregnant pegasus, a flying monkey with a sprained wing, a centaur with Cushing's disease, and a unicorn with a sweet tooth) who rely on him for their medical care and shelter from the outside world. When a deadly basilisk threatens the town, Jonathan and his new friends must balance the dangerous creature's needs against the risk to the community.