Canaan Creek, South Carolina, in the 1950s is a tiny town where the close-knit African-American community is united by long-term friendships and church ties. Bonnie Wilder has lived here, on Blackberry Corner, all her life, and would be content but for her deep desire to have a child. She and her husband Naz cannot conceive, and he refuses to adopt. Even the support of her outrageous best friend Thora--to whom Bonnie tells everything--can' t help fill the emptiness inside her.

Then Naz finds a blanketed infant on the banks of Canaan Creek, and suddenly Bonnie's life is transformed. She has found her calling. Together with Thora and the rest of the hilarious, tough, and all-too-human women from her church group, Bonnie creates an underground railroad for unwanted babies. But one of these precious gifts will come back to haunt her: a deception begun in good faith comes full circle, ultimately forcing Bonnie to find the courage to confront a difficult truth at the center of her own life.