As the head of the Catholic Church, the Vatican has investigated religious mysteries for authenticity for centuries. The present day is no exception. A multinational team has been dispatched on a globe-trotting mission to investigate a warning issued by the Virgin Mary. The inhabitants of the earth must change their ways, she tells us, or her Son will return with a vengeance. The message goes unheeded.

The Vatican Investigation Division descends on a monastery in Oregon, as the world prepares for war. A weapon designed to split the world in half is built and powered up in Syria. As the team divides, one half goes to the United States while the other half heads to the Middle East to both authenticate the message and stop Armageddon. Between the two, they must find a way to prevent a war so destructive it would destroy all life as we know it.