November, 1853. Inspector Field has summoned his friends Charles Dickens and Wilkie Collins to examine a body found in an attic studio, its throat cut. Around the body lie the lacerated fragments of canvas of a painting titled A Winter of Despair.

On closer examination, Wilkie realizes he recognizes the victim, for he had been due to dine with him that very evening. The dead man is Edwin Milton-Hayes, one of Wilkie's brother Charley's artist friends. But what is the significance of the strange series of faceless paintings Milton-Hayes had been worked on when he died? And why is Charley acting so strangely?

With his own brother under suspicion of murder, Wilkie Collins and Charles Dickens set out to uncover the truth. What secrets lie among the close-knit group of Pre-Raphaelite painters who were the dead man's friends? And who is the killer in their midst?